为解决慢性髓性白血病（CML）患者白血病干细胞（CML LSCs）对酪氨酸激酶抑制剂（TKI）不敏感、难以实现无治疗缓解（TFR）的问题，研究人员开展 TM5614 联合 TKI 治疗 CML 的研究。结果显示联合疗法安全有效，有望实现 TFR，意义重大。 在血液疾病的领域中，慢性髓 ...

本文聚焦慢性髓性白血病（CML）研究，介绍下一代测序（NGS）技术。其可深入剖析 CML 遗传复杂性，检测 BCR::ABL1 融合基因及相关突变，助力研究微小残留病（MRD） 。但该技术存在数据解读、标准化和成本等问题。未来，NGS 有望优化 CML 治疗策略。 下一代测序 ...

Imatinib is a highly effective therapy for chronic phase-chronic myeloid leukaemia (CP-CML) patients; however, responses to frontline imatinib are variable. The human organic cation transporter 1 ...

Chronic myeloid leukemia (CML) is a type of blood cancer that people may also refer to as chronic myelogenous leukemia. Doctors diagnose the stage of CML based on the number of leukemia cells, or ...

Medications for CML directly destroy cancer cells or help the body’s immune system attack cancer cells to prevent them from growing. Medications may not cure CML, so people may need to continue taking ...

Chronic myelogenous leukemia (CML) is a cancer that affects your blood cells and bone marrow -- the soft part inside your bones where blood cells are made. You may also hear your doctor call it ...

Doctors use molecular responses to monitor the effectiveness of CML treatment. A major molecular response is when the amount of the abnormal BCR–ABL gene in your blood and bone marrow is lowered to ...

Unprecedented Phase 1 CML efficacy data and potential best-in-disease profile of TERN-701 featured in ASH 2025 abstract Upcoming ASH oral presentation to feature expanded and updated dataset from ...