This article introduces the field of bioinformatics and its importance as a cornerstone of biological research, as well as ...

The concept of a bioinformatic framework is exemplified by sequence databases. DNA sequences provide a one-dimensional framework to which additional information concerning structure and function can ...

NGS enables the in-depth analysis of the genome and the identification and investigation of disease-associated variants–especially when workflows include target enrichment, which focuses on specific ...

The precise definition of bioinformatics has always been a matter of some debate. Although some use a narrow definition which limits it to the analysis of genome sequences (and more recently ...

GenAI models have revolutionized bioinformatics applications by learning from massive biological datasets, genomic sequences, protein structures, and single-cell transcriptomes, without requiring ...

Historical introduction and overview -- Collecting and storing sequences in the laboratory -- Alignment of pairs of sequences -- Introduction to probability and statistical analysis of sequence ...

Proteins, with their extraordinary diversity of structure and function, pose some of the toughest problems in the field of bioinformatics, giving rise to a growing arsenal of computational tools for ...

This course is a high-content introduction to scripting and programming with applications in bioinformatics. It is appropriate for students with little previous programming experience. The course ...

The UK National Health Service is collaborating with university partners to transform public health and personalized medicine with the power of high performance computing. Bioscience teams at NHS and ...