本研究通过实时成像技术揭示ADP/ATP载体（AAC）与ATP合酶的功能性相互作用如何精确调控线粒体内膜H+流分布，为能量平衡失调 ...

Researchers used a novel phosphate-activation reagent, 2-MeImIm-Cl, in an improved coupling reaction to increase the yield of ADP- or ATP-containing molecules. Unlike traditional reactions, the ...

Hsp90 plays a central role in cell homeostasis by assisting folding and maturation of a large variety of clients. It is a homo-dimer, which functions via hydrolysis of ATP-coupled to conformational ...

Key nuclear processes in eukaryotes, including DNA replication, repair, and gene regulation, require extensive chromatin remodeling catalyzed by energy-consuming enzymes. It remains unclear how the ...

Adenosine 5′-triphosphate, abbreviated ATP and usually expressed without the 5′-, is an important “energy molecule” found in all life forms. Specifically, it is a coenzyme that works with enzymes such ...

A simple two-carbon compound may have been a crucial player in the evolution of metabolism before the advent of cells, according to a new study. The finding potentially sheds light on the earliest ...